【 文献重点摘要 】

Background

Striae Distensae (SD) is a very common dermatologic condition. We evaluated the effectiveness and safety of a novel non-ablative fractional 1565 nm laser (ResurFX) on the appearance of SD.

Materials and methods

Twelve Caucasian subjects with various stages of SD received three non-ablative laser treatments. Each treatment consisted of two different laser settings, in order to achieve a demarcated dense impact together with a diffused deep impact. Three months after the last treatment, SD improvement was assessed by blinded and non-blinded reviewers using clinical images and 3D image analyses.

Results

Good clinical improvement (between 51% and 75%) was observed in all patients. Most patients showed improvement of > 50% in the volume of depressions and in lesion color (91.7% and 83.3% of patients, respectively). The average pain during treatment was generally defined as tolerable and the average downtime was 4 days. Transient erythema and severe edema were noted immediately after the procedure, but long-lasting or severe adverse effects were not observed. All patients noted a good improvement and were satisfied with the treatment and the results.

Conclusions

The treatment with the 1565 nm ResurFX laser resulted in improved pigmentation, volume, and textural appearance of SD.

Key Words

1565 nm, non-ablative fractional, stretch marks

背景

犬瘟热是一种非常常见的皮肤病。我们评估了一种新型非消融分数1565纳米激光(ResurFX)对SD外观的有效性和安全性。

材料和方法

12名不同发展阶段的高加索受试者接受了三种非消融性激光治疗。每种处理包括两种不同的激光设置，以实现一个清晰的密集冲击和一个分散的深度冲击。最后一次治疗后三个月，由盲法和非盲法审查者使用临床图像和3D图像分析评估SD改善。

结果

所有患者均获得良好的临床改善(51%-75%)。大多数患者表现出凹陷体积和病变颜色改善超过50%(分别为91.7%和83.3%)。治疗期间的平均疼痛通常被定义为可忍受的，平均停工时间为4天。手术后立即出现短暂红斑和严重水肿，但未观察到长期或严重的不良反应。所有患者都注意到了良好的改善，并对治疗和结果感到满意。

结论

1565纳米激光治疗可改善SD大鼠的色素沉着、体积和质地。

关键词

1565纳米，非烧蚀分数，妊娠纹