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Botulinum Toxin Off-Label Use in Dermatology: A Review
Campanati Anna
简介
【 文献重点摘要 】
Background: Botulinum toxin is a neurotoxin produced by the bacterium Clostridium botulinum which causes a flaccid muscle paralysis. It is currently used for aesthetic treatments and in the focal hyperhidrosis. Recently, botulinum toxin has also been used experimentally in many other dermatological conditions with good results.
Objective: To review and analyze the possible botulinum toxin off-label applications published.
Methods: A retrospective review of the published data was conducted.
Conclusions: this potent drug can lead to several off-label indications of interest for dermatologists. Further clinical trials are still needed to better understand the real efficacy and safety of these applications and to standardize injection and dose protocols.
Keywords: Botulinum toxin, Off-label therapy, Keloids, Hidradenitis suppurativa, Folds dermatitis
背景：肉毒毒素是肉毒梭菌产生的一种神经毒素，可引起松弛性肌肉瘫痪。它目前被用于美容治疗和局灶性多汗症。最近，肉毒杆菌毒素也被用于许多其他皮肤病的实验，取得了良好的效果。
目的：回顾和分析肉毒毒素可能在标签外的应用。
方法：对已发表的资料进行回顾性分析。
结论：这种强效药物可以导致皮肤科医生感兴趣的几个标签外适应症。还需要进一步的临床试验来更好地了解这些应用的真正有效性和安全性，并使注射和剂量方案标准化。
关键词：肉毒毒素；标签外治疗；瘢痕疙瘩；化脓性汗腺炎；折叠性皮炎
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