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【临床并发症文献】两例透明质酸基填充物注射剂的不良反应
Two Cases of Adverse Reactions of
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【 文献重点摘要 】
Hyaluronic acid (HA) is one of the natural components of the human body with high biocompatibility, biodegradability, and nonimmunogenicity, which makes it the ideal biomedical filling agent currently available. However, for many medical practitioners, HA filler injections remain a relatively new item to carry out. Learning while practicing, it is inevitable to encounter some difficulties and adverse reactions in its application. Here we report two cases of adverse reactions to HA-based filler injections, including anaphylactic reaction on the face and vascular thrombosis after augmentation rhinoplasty with HA filler. In this report, we highlight the management and prevention of the adverse reactions, especially in case 2, because vascular thrombosis is one of the severe complications and injectors should know how to avoid it and how to deal with it, thereby increasing the safety of HA-based procedures.
透明质酸(HA)是人体的天然成分之一，具有很高的生物相容性、生物降解性和非免疫原性，是目前理想的生物医学填充剂。然而，对许多医生来说，医管局填充剂注射仍然是一个相对较新的项目。边学边练，在应用中难免会遇到一些困难和不良反应。本文报告两例HA填充物注射的不良反应，包括面部过敏反应和HA填充物隆鼻术后血管血栓形成。在本报告中，我们强调不良反应的管理和预防，特别是在病例2中，因为血管血栓形成是严重的并发症之一，注射者应该知道如何避免和处理它，从而增加基于HA的手术的安全性。
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