眉上皱纹和A型肉毒毒素
Supraciliary wrinkles and botulinum toxin A
【 文献重点摘要 】
Background
Injection of botulinum toxin into certain areas of face that carry a high risk of ptosis (danger zone) needs caution in application. An example is the lateral forehead, particularly the lower portion.
Aim
In this study, we evaluated the efficacy and safety of treating supraciliary wrinkles in the lower lateral forehead by injections of botulinum toxin at the temporal hairline, keeping a reasonable distance from danger zone.
Methods
In this randomized clinical trial, 40 women (mean age 35 years) were selected and divided into two groups, A and B. both groups were treated with botulinum toxin to treat wrinkles in the frown area, as well as frontal lines and lateral canthus lines. Group B received extra injections at each temporal line for treatment of supraciliary wrinkles.
Results
There was a significant difference in total wrinkle number and mean number of wrinkles between the two groups after injections (paired t-test, P < 0.01). No ptosis was seen in either group.
Conclusions
Injection of botulinum toxin type A through the temporal hairline to correct supraciliary wrinkles seems to be safe and effective.
背景
将肉毒杆菌毒素注射到面部某些具有上睑下垂高风险的区域(危险区)需要谨慎使用。侧额就是一个例子,特别是下部。
目的
评价颞部发际线注射肉毒毒素治疗额部下侧眉上皱纹的疗效和安全性,并与危险区保持合理距离。
方法
随机选择40例女性(平均年龄35岁),随机分为A、B两组,分别用肉毒毒素治疗眉部皱纹、额部皱纹和外眼角皱纹。B组在每条颞线上额外注射治疗眉上皱纹。
结果
两组患者注射后皱纹总数和平均皱纹数比较,差异有显著性意义(配对t检验,P<0.01)。两组均未见上睑下垂。
结论
A型肉毒毒素经颞叶发际注射矫正眉上皱纹安全有效。