【 文献重点摘要 】
 

Background: Injection of soft-tissue fillers into the facial fat compartments is frequently performed to ameliorate the signs of facial aging. This study was designed to investigate the functional anatomy of the deep facial fat compartments and to provide information on the effects of injected material in relation to age and gender differences.

Methods: Forty fresh frozen cephalic specimens of 17 male and 23 female Caucasian body donors (mean age, 76.9 ± 13.1 years; mean body mass index, 23.6 ± 5.3 kg/m2) were investigated. Computed tomographic and magnetic resonance imaging procedures were carried out using colored contrast-enhanced materials with rheologic properties similar to commercially available soft-tissue fillers. Anatomical dissections were performed to guide conclusions.

Results: No statistically significant influences of age or gender were detected in the investigated sample. Increased amounts of injected contrast agent did not correlate with inferior displacement of the material in any of the investigated compartments: deep pyriform, deep medial cheek, deep lateral cheek, deep nasolabial (located within the premaxillary space), and the medial and lateral sub–orbicularis oculi fat.

Conclusions: Increasing volume in the deep midfacial fat compartments did not cause inferior displacement of the injected material. This underscores the role of deep soft-tissue filler injections (i.e., in contact with the bone) in providing support for overlying structures and resulting in anterior projection.

背景：经常在面部脂肪腔内注射软组织填充物，以改善面部衰老的迹象。本研究旨在研究面部深层脂肪室的功能解剖学，并提供有关注射材料与年龄和性别差异的影响的信息。

方法：40例新鲜冷冻头颅标本，男17例，女23例，平均年龄(76.9±13.1)岁，平均体重指数(23.6±5.3)kg/m2。计算机断层扫描和磁共振成像程序是使用彩色对比增强材料进行的，这些材料的流变特性类似于市场上可以买到的软组织填充物。进行解剖学解剖以指导结论。

结果：在所调查的样本中，年龄和性别均未发现有统计学意义的影响。造影剂注射量的增加与所调查的任何一个间隔的材料下移无关：深梨形、深内侧颊、深外侧颊、深鼻唇(位于前颌间隙内)以及眼轮匝肌内侧和外侧脂肪。

结论：面中部深层脂肪室容积的增加不会引起注射材料的下移。这强调了深层软组织填充物注射(即与骨骼接触)在提供对覆盖结构的支持和导致前投影方面的作用。