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【临床并发症文献】局部冷却法治疗透明质酸注射后栓塞并发症案例分析
Local Cooling as a Step of Treatment for
简介
【 文献重点摘要 】
Hyaluronic acid injection is 1 of the most popular procedures in facial rejuvenation and augmentation. It is widely popular in the cosmetic surgery due to several advantages, which include rapid effect, minimal injury, and a short postoperative recovery period. With continuous increase in hyaluronic acid injections, many cases of hyaluronic acid injection-induced embolism have been reported. At present, methods for early treatment of hyaluronic acid injection–induced embolism include local injection of hyaluronidase, topical application of nitroglycerin ointment, massage, hot compression, and intravenous injections of antibiotics and hormones. Although early warm massage may facilitate hyaluronic acid degradation by hyaluronidase, local application of heat will also increase metabolic rate in the tissue, thereby reducing the ischemic tolerance of the tissue. Therefore, in this study, warm massage was limited to the first 30 minutes after hyaluronidase injection and was followed by local cooling using a gauze pad soaked with antibiotic saline solution. Excellent therapeutic effects were achieved with this approach. The methods of treatment for tissue ischemia caused by hyaluronic acid injection–induced embolism and clinical cases are introduced in the article.
透明质酸注射是面部年轻化和丰满术中最受欢迎的手术之一。它具有见效快、创伤小、术后恢复期短等优点，在整形外科中得到广泛应用。随着透明质酸注射量的不断增加，透明质酸注射所致栓塞的报道越来越多。目前，透明质酸注射致栓塞的早期治疗方法包括局部注射透明质酸酶、局部涂抹硝酸甘油软膏、按摩、热敷、静脉注射抗生素和激素。虽然早期热按摩可能会促进透明质酸被透明质酸酶降解，但局部加热也会增加组织的代谢率，从而降低组织的缺血耐受性。因此，在这项研究中，热按摩仅限于注射透明质酸酶后的前30分钟，然后使用浸泡了抗生素生理盐水的纱布垫进行局部降温。该入路取得了良好的治疗效果。本文介绍了透明质酸注射致栓塞所致组织缺血的治疗方法及临床病例。
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