【 文献重点摘要 】
 

Radiesse® (Bioform Inc, USA) is a sterile, latex-free, non-pyrogenic, semi-solid, cohesive subdermal, injectable implant, whose principal component is synthetic calcium hydroxylapatite, a biocompatible material with over 20 years of use in medicine. The semi-solid nature of the product is created by suspending calcium hydroxylapatite microspheres of 25–45 microns diameter in a gel carrier of carboxymethylcellulose. The product has FDA approval for esthetic facial augmentation in the US. Such approval includes the long-lasting correction of moderate to severe facial wrinkles and folds and the treatment of facial fat loss due to immunodeficiency virus infection. Diverse facial regions can be injected in order to ameliorate or enhance some features: glabellar lines, subdermal support of the brows, malar and buccal fat pads, tear troughs, nasolabial folds, nose, lips, perioral region, marionette lines, oral commisures and chin among others, as well as saucerized acne scars. Other medical indications include nipple projection for nipple areolar reconstruction, urinary incontinence, vesicoureteral reflux, vocal cord augmentation, and use as a radiographic tissue marker. The average lasting result is from 12 to 18 months. Radiesse can be considered an effective soft-tissue filler for overall longevity, biocompatibility, and low rate of side effects.

Keywords

hydroxylapatite, facial augmentation, Radiesse

Radiesse®(Bioform Inc，美国)是一种无菌、无乳胶、不致热、半固体、有粘合力的皮下可注射植入物，其主要成分是合成羟基磷灰石，这是一种生物相容性材料，已在医学上使用了20多年。该产品的半固态是通过将直径为25-45微米的羟基磷灰石微球悬浮在羧甲基纤维素的凝胶载体中而产生的。该产品已获得FDA批准，可在美国进行美容美容。这种批准包括对中到重度面部皱纹和皱褶的长期纠正，以及治疗由于免疫缺陷病毒感染而导致的面部脂肪减少。可以注射不同的面部区域，以改善或增强某些特征：眉毛间纹、眉毛皮下支撑、颧脂和颊脂垫、泪沟、鼻唇皱褶、鼻子、嘴唇、口周区、提线、口角和下巴等，以及碟状痤疮疤痕。其他医学适应症包括乳头投影，用于乳头乳晕重建，尿失禁，膀胱输尿管返流，声带增强，以及用作放射学组织标记。平均持续时间为12至18个月。Radiesse可以被认为是一种有效的软组织填充剂，总体寿命长，生物相容性好，副作用少。

关键词

羟基磷灰石，面部美容，辐射